Jim Xiao

"Build the event you wish existed" That's what we at Monadical did last week at #NYTW. We wanted an AI Engineers discussion for Engineers. There's always a lot of events out there for VCs to network, or for startups to learn about G2M, but very little on lessons learned from actual engineers in the field. So that's the event we hosted. Big thank yous to our awesome panel, Roy Pereira, Ben Cohen and Corey J. Gallon. Here's the key takeaways and the AI tools we're using. 🚀 All three panelists independently called AI Agents the most transformative LLM application they’ve used. They specifically called out Claude 3.5 Sonnet for its accuracy and reliability. 🪨 We dug into how LLMs are “jagged”, not general. They can be shockingly good at some tasks and completely fail at others. Everyone agreed: good evaluations are critical (and hard.) 🧪 Corey noted how public benchmarks and reality are two different things. Most public evals are saturated or gamed. ♊ Ben emphasized that AI projects are actually two projects: building the tool and building the evaluation process. 🧱 We explored how falling dev costs may impact startup defensibility and labor demand. Roy shared that founders are already shifting strategies in response. ⚒️ In a world of daily AI launches, the panel discussed how they decide what’s worth attention, and what’s just noise. They called out tools like Goose, Aider, Claude Code, and Monadical’s own Cubbi, which helps run agentic workflows safely in dev environments. (links in the comments). CTA: What would you want to hear in an AI Applied Engineering talk you attended?

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I’m lucky to work alongside colleagues like Richard Fruehauf, who constantly push my thinking. His latest piece unpacks why U.S. robotics and drone manufacturing faces uphill economics, and how public policy can help turn the tide. One key takeaway: 232 tariffs on robotics imports could help reset the economics that are holding back U.S. investment and production. It’s a sharp perspective on how policy can shape the future of advanced tech here at home. Well worth a read: https://lnkd.in/edMPTQPQ Richard Fruehauf, Robert J. Szczerba, Michael Lutzky, Edward Ovando, Karl Sanchack, Herman Herman, Jeff Legault, Phil English, Richard Fruehauf, Ryan Aument, Michael Guido, Sheila Fitzgerald Sterrett, David McCormick

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Thrilled to see Prosoma join the CRB Health Tech SGEIC portfolio alongside Verge HealthTech Fund and IMPACT Partners. Tackling the critical mental health needs of oncology patients with an evidence-based, reimbursed digital therapeutic already making strides in Europe—and now expanding to the U.S. market. Looking forward to supporting their journey in value-based care and global growth. #DigitalHealth #Oncology #MentalHealth #VentureCapital #CRBInvests #HealthInnovation

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Congratulations to Guy Ezekiel, Maya Perl, and the entire Zorro team on their $20 million Series A funding round to continue their mission to revolutionize healthcare benefits by making high-quality, affordable healthcare accessible to all! This is especially exciting since Guy and Maya used to be at Pitango. They've now build this incredible company, and I'm proud to support them from day one and see them grow the next-generation benefits administration platform that is transforming how America’s workers plan, pay and save for healthcare. As Guy said: “Healthcare [in America] is not one-size-fits-all, and we’re past due for an alternative to the skyrocketing costs of group health plans. Zorro is building a new future where health and wealth planning are integrated, giving employers predictability without sacrificing quality and individuals the autonomy to make smart, personalized decisions for themselves and their families.” LINK to Axios article: https://lnkd.in/d8XN9TXP   #Pitango Pitango Entrée Capital , 10D

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Embracing Innovation in Family Health Management The launch of Luffu by Fitbit founders exemplifies the relentless pursuit of innovation in health technology. By utilizing AI to track family health patterns and flagging significant changes, this platform promises to enhance preventative care. At ElevenX Capital, we recognize the potential of such solutions in transforming family health management. As investors, how important do you believe it is to integrate AI into health monitoring for long-term wellbeing? #investing #innovation #venturecapital #entrepreneurship

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AI and Health Tech in Focus   AI Tool Used to Help Predict Postpartum Depression Researchers at Harvard University’s Massachusetts General Hospital have developed an AI tool that helps predict the risk of postpartum depression (PPD) before discharge from the hospital. Approximately 15% of women suffer from PPD which is responsible for suicide and self-harm and about 10% of all pregnancy related deaths. The researchers trained the algorithm based on about 29,000 mothers using electronic health records data including medical history, medication data, age, race, ethnicity, education, marital status, insurance type, number of births, mode of delivery, number of prenatal visits, length of delivery stay as well as an existing but more modest predictability score for PPD called EPDS. Incorporating this data resulted in an ability to predict more than three times the baseline risk of PPD. Using this model can help care teams identify those at risk for PPD and provide resources and support services such as referral to social workers, psychotherapy, psychiatry or medical therapy before they have an impact on the mother, child and their families. VC Investors are always adjusting their "Play Book" with a variety of options for investing. Mikal Ventures is one of those alternatives, offering curated solutions to real world problems. Reach out if you have questions on how we can be of assistance and bookmark https://mikalventures.com/ for additional insights and information.

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Check out the latest from Limbic - their breakthrough study in Nature Portfolio, shows how Limbic turns frontier language models into behavioral health specialists. In their pre-registered, double-blind randomized trial they showed that: 1️⃣ Adding the Limbic Layer improves AI-led therapy performance by 43% 2️⃣ Clinicians preferred Limbic over general-purpose LLMs 83% of the time 3️⃣ 74% of Limbic's AI sessions ranked among the top 10% of therapists 4️⃣ Patients rate the Limbic experience as comparable to clinician-led sessions Amazing stuff from Ross Harper and Sebastiaan de Vries - delighted to have them in the Entrepreneurs First portfolio.

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Honored and excited to partner with Drew Baglino and the incredible team at Heron Power as they re-imagine the electric grid for the modern world. Power in America is not zero sum. We deserve access to cheap and abundant electricity and we should win the AI race. And we must build the capacity to manufacture critical technology here at home. When faced with existential challenges, we deploy technology against them. And we win.

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